PROPYLENE GLYCOL
MSDS Number: P6928 --- Effective Date: 02/25/99
1. Product Identification
Synonyms: 1,2-propanediol; 1,2-dihdroxypropane; methyl
glycol; methylethylene glycol
CAS No.: 57-55-6
Molecular
Weight: 76.09
Chemical Formula: CH3CHOHCH2OH
Product
Codes:
J.T. Baker: 9402, 9403, U510
Mallinckrodt: 1925, 6263
Other Information
NFPA Ratings: Health: 0 Flammability: 1
Reactivity: 0
Label Hazard Warning:
CAUTION! MAY CAUSE
IRRITATION TO SKIN AND EYES.
Label Precautions:
Avoid contact
with eyes, skin and clothing.
Wash thoroughly after handling.
Label
First Aid:
In case of contact, immediately flush skin or eyes with
plenty of water for at least 15 minutes. Call a physician if irritation
develops or persists.
Product Use:
Laboratory Reagent.
Hazards Identification
Emergency Overview
--------------------------
CAUTION! MAY CAUSE IRRITATION TO SKIN AND EYES.
J.T.
Baker SAF-T-DATA(tm) Ratings (Provided here for your
convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 0 - None
Flammability Rating: 1 - Slight
Reactivity
Rating: 1 - Slight
Contact Rating: 1 - Slight
Lab Protective Equip:
GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
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Potential Health Effects
----------------------------------
Inhalation:
No adverse health effects via inhalation.
Ingestion:
Relatively toxic. Ingestion of sizable amount
(over 100ml) may cause gastrointestinal upset and temporary central
nervous system depression. Effects appear more severe in individuals with
kidney problems.
Skin Contact:
Irritant and defatting
agent, especially on prolonged contact.
Eye Contact:
May cause
transitory stinging and tearing.
Chronic Exposure:
Lactic
acidosis, stupor and seizures have been reported following chronic ingestion Kidney
disorders, skin disorders, eye tissue damage.
Aggravation of Pre-existing Conditions:
Kidney disorders,
skin disorders, eye tissue damage.
First Aid Measures
Inhalation:
Remove to fresh air. Not expected to
require first aid measures.
Ingestion:
Not expected to require
first aid measures. Give several glasses of water to drink to dilute. If large
amounts were swallowed, get medical advice.
Skin Contact:
Remove any contaminated clothing. Wash skin with soap and water for at
least 15 minutes. Get medical attention if irritation develops or persists.
Eye Contact:
In case of contact, immediately flush eyes with
plenty of water for at least 15 minutes, lifting upper and lower eyelids
occasionally. Call a physician if irritation persists.
Note to
Physician:
In case of ingestion, monitor for acidosis and central
nervous system changes. Exposed persons with previous kidney dysfunction may
require special treatment.
Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer!
Handling and Storage
Protect container from physical damage. Store in a cool, dry,
ventilated area away from sources of heat, moisture, and incompatible
substances. Containers of this material may be hazardous when empty since they
retain product residues (vapors, liquid); observe all warnings and precautions
listed for the product.
Exposure Controls/Personal Protection
Airborne Exposure Limits:
AIHA Workplace Environmental
Exposure Level (WEEL): Vapor and Aerosol = 50ppm; Aerosol, only = 10mg/m3.
Ventilation System:
A system of local and/or general exhaust is
recommended to keep employee exposures below the Airborne Exposure Limits.
Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into
the general work area. Please refer to the ACGIH document, Industrial
Ventilation, A Manual of Recommended Practices, most recent edition, for
details.
Personal Respirators (NIOSH Approved):
If the exposure
limit is exceeded, a half-face respirator with an organic vapor cartridge and
particulate filter (NIOSH type P95 or R95 filter) may be worn for up to ten
times the exposure limit or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest. A
full-face piece respirator with an organic vapor cartridge and particulate
filter (NIOSH P100 or R100 filter) may be worn up to 50 times the exposure
limit, or the maximum use concentration specified by the appropriate
regulatory agency or respirator supplier, whichever is lowest. Please note
that N series filters are not recommended for this material. For emergencies
or instances where the exposure levels are not known, use a full-face piece
positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators
do not protect workers in oxygen-deficient atmospheres.
Skin
Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash
fountain and quick-drench facilities in work area.
Physical and Chemical Properties
Appearance:
Clear oily liquid.
Odor:
Odorless.
Solubility:
Miscible in water.
Specific
Gravity:
1.0361 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
188.2C (370F)
Melting Point:
-59C
(-74F)
Vapor Density (Air=1):
2.6
Vapor Pressure (mm
Hg):
0.129 @ 25C (77F)
Evaporation Rate (BuAc=1):
0.01
Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Carbon dioxide and
carbon monoxide may form when heated to decomposition. Aldehydes or lactic,
pyruvic or acetic acids may also be formed.
Hazardous
Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents.
Conditions to Avoid:
Heat, flames,
ignition sources and incompatibles.
Toxicological Information
Oral rat LD50: 20g/kg. Skin rabbit LD50: 20.8g/kg.
Irritation: Eye rabbit/Draize, 500 mg/24H mild.
Investigated as a
mutagen and reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Propylene Glycol (57-55-6) Slight Probable None
Ecological Information
Environmental Fate:
When released into the soil, this
material is expected to readily biodegrade. When released into the soil, this
material is expected to leach into groundwater. When released into water, this
material is expected to readily biodegrade. When released into the air, this
material is expected to be readily degraded by reaction with photochemically
produced hydroxyl radicals. When released into the air, this material is
expected to have a half-life between 1 and 10 days.
Environmental
Toxicity:
No information found.
Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
managed in an appropriate and approved waste disposal facility. Processing,
use or contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations. Dispose of container and unused contents in accordance with
federal, state and local requirements.
Transport Information
Not regulated.
Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Propylene Glycol (57-55-6) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Propylene Glycol (57-55-6) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Propylene Glycol (57-55-6) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Propylene Glycol (57-55-6) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This
MSDS has been prepared according to the hazard criteria of the Controlled
Products Regulations (CPR) and the MSDS contains all of the information
required by the CPR.
Revision Information:
MSDS Section(s) changed since last
revision of document include: 3, 8, 9.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Strategic Services Division
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